MMWR Early Release

Allergic Reactions Including Anaphylaxis After Receipt of the First Dose of Moderna COVID-19 Vaccine

Jan 22, 2021 | Beth Hess

This CDC MMWR summarizes the clinical and epidemiologic characteristics of people with a severe allergic reaction known as anaphylaxis who received the first dose of Moderna COVID-19 vaccine in the United States during the first three weeks of vaccine administration. Early safety monitoring of the Moderna COVID-19 vaccine detected 10 people with anaphylaxis among more than 4 million first doses of Moderna COVID-19 vaccine that were administered. Among those with follow-up information available, all recovered or were discharged home.


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