In support of the National Prevention Strategy, ASTHO produced this innovative resource to educate and empower public health leaders to promote a Health in All Policies (HiAP) approach to policy-making and program development. By collaborating across multiple sectors to address health disparities and empower individuals, promoting healthy communities, and ensuring quality clinical and community preventive services, we can increase the number of Americans who are healthy at every stage of life. A description of the National Prevention Strategy is enclosed along with key talking points to explain a HiAP approach to other leaders in your state or localitys government, characteristics of successful cross-sector collaboration, and a collection of state stories meant to inspire you into action! The stories are organized based on the following characteristics of successful cross-sector collaboration: Creating shared goals Engaging partners early/ developing partner relationships Defining a common language Activating the community Leveraging funding/ investments