OD2A-funded jurisdictions work to monitor and evaluate their surveillance and prevention efforts. Jurisdictions work collaboratively with CDC to evaluate the implementation and impact of each of the OD2A strategies. The evaluation of these efforts is essential to ensure program fidelity, efficacy, and efficiency. The following OD2A evaluation profiles can be tailored to the evaluation needs of programs and initiatives to ensure they are implemented effectively for desired outcomes. The profiles contain guidance on the types of evaluation questions, indicators, data sources, and data collection methods that can be used to evaluate the specified topics and activities. State and local health departments, community-based organizations, medical and healthcare professionals, and program managers can use these profiles to determine how well programs and initiatives are being implemented and the effectiveness on desired outcomes.