Multidrug-resistant organisms (MDROs) are germs, often bacteria, that are resistant to one or more antimicrobial drugs. In most instances, MDRO infections have signs and symptoms similar to infections caused by microbes that can be treated with antimicrobial drugs; however, options for treating patients with MDRO infections are often extremely limited. As such, MDROs are associated with increased lengths of hospital stay, costs, and mortality. Monitoring, preventing, and controlling MDROs is a national priority, which requires healthcare facilities as well as federal, state, and local agencies, including health departments, to assume responsibility.*
In support of this mission to mitigate the spread and impact of MDROs, NACCHO created a series of resources on specific MDRO threats that were highly requested by our membership. Local health departments can utilize these fact sheets, decision trees, and webinar resources within their healthcare facilities to inform preventive and response efforts for MDROs.
* You can locate the full NACCHO Board Statement of Policy on MDROs here.
Fact Sheets
- Candida Auris (C. Auris)
- Carbapenem Resistant Acinetobacter baumannii (CRAB)
- Carbapenem Resistant Enterobacterales (CRE)
- Extended Spectrum Beta Lactamase (ESBL)
Decision Trees
- Candida Auris (C. Auris)
- Carbapenem Resistant Acinetobacter baumannii (CRAB)
- Carbapenem Resistant Enterobacterales (CRE)
- Extended Spectrum Beta Lactamase (ESBL)
- Transmission-Based Precautions for Acute Care Facilities
- Transmission-Based Precautions for Nursing Homes**
** Please note that the decision tree for nursing homes refers strictly to nursing homes. Guidance from this document should not be extrapolated to other long-term care facilities.
Webinar Resources
- Full Webinar Zoom Recording: Multi-drug resistant organisms: a primer on CRE/CP-CRE, C. Auris, ESBL & CRAB
- Slides: Multi-Drug Resistant Organisms: a Primer on CRE-CP-CRE, C. auris, ESBL & CRAB
- Slides: Introduction to MDRO’s
- Slides: C. auris
- Slides: CRAB
- Slides: CRE
- Slides: ESBL
- Slides: Addressing MDROs Next Steps