On September 18, the Centers for Disease Control and Prevention (CDC) issued a Health Alert Network (HAN) Health Advisory about a new outbreak of Ebola virus disease (EVD) in the Democratic Republic of the Congo (DRC). EVD is a severe illness and is often fatal.

Currently, no suspected, probable, or confirmed EVD cases related to this outbreak have been reported in the United States or outside of the DRC. The risk of spread to the United States is considered low at this time. As a precaution, this Health Advisory summarizes CDC recommendations for U.S. public health departments, clinical laboratories, and healthcare workers about potential EVD case identification, testing, and biosafety considerations in clinical laboratories.

On September 8, 2025, CDC issued a Travel Health Notice for people traveling to the DRC. CDC recommends that all travelers to the affected health zones in DRC avoid contact with ill people during travel and monitor themselves for symptoms of EVD while in the outbreak area and for 21 days after leaving. Travelers who develop symptoms during this time should self-isolate and contact local health authorities or a clinician. At this time, CDC is not recommending additional assessments or monitoring of travelers arriving from DRC by the jurisdictional health departments unless mentioned in the existing VHF guidance provided below.

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